Intranasal vaccination with extracellular serine proteases of Leishmania amazonensis confers protective immunity to BALB/c mice against infection

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作者
Herbert Leonel de Matos Guedes
Beatriz Lilian da Silva Costa
Suzana Passos Chaves
Daniel Cláudio de Oliveira Gomes
Joshua Daniel Nosanchuk
Salvatore Giovanni De Simone
Bartira Rossi-Bergmann
机构
[1] Universidade Federal do Rio de Janeiro,Laboratório de Imunofarmacologia, Instituto de Biofísica Carlos Chagas Filho
[2] FIOCRUZ-Oswaldo Cruz Foundation. Center for Technological Development in Health (CDTS)/National Institute of Science and Technology of Innovation on Diseases of Neglected Populations,Laboratório de Imunologia Celular e Molecular, Núcleo de Doenças Infeccio
[3] Universidade Federal do Espírito Santo,Departments of Medicine and Microbiology and Immunology, Albert Einstein College of Medicine
[4] Yeshiva University,Núcleo Multidisciplinar de Pesquisa UFRJ – Xerém em Biologia (NUMPEX
[5] Polo Avançado de Xerém – Universidade Federal do Rio de Janeiro,BIO)
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关键词
Murine cutaneous leishmaniasis; Mucosal vaccine; Intranasal route; Extracellular serine proteases;
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