A new class of RNAs and the centrosomal hypothesis of cell aging

被引:0
|
作者
Chichinadze K. [1 ,2 ]
Tkemaladze J. [3 ]
Lazarashvili A. [3 ]
机构
[1] Beritashvili Center for Experimental Biomedicine, Gotua str. 14, Tbilisi
[2] I. Javakhishvili Tbilisi State University, Chavchavadze ave. 5, Tbilisi
[3] Systemic Research Center, Vaja-Pshavela ave. 18A, Tbilisi
关键词
Cell aging; Centrosome; RNA;
D O I
10.1134/S2079057012040054
中图分类号
学科分类号
摘要
The recent discovery of a new class of RNAs, which are called centrosomal RNAs, in the centrosome is indirect proof of the centrosome hypothesis of cell differentiation and aging, in our opinion. The presence of a reverse transcriptase domain in RNAs of this class and the high specificity of this RNA for the organoid may make the centrosome a site for information storage and reproduction. The ability of this organelle to fulfill these functions is one of the basic postulates of the centrosome hypothesis of cell differentiation and aging. © Pleiades Publishing, Ltd., 2012.
引用
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页码:287 / 291
页数:4
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