Sildenafil augments pelvic nerve‐mediated female genital sexual arousal in the anesthetized rabbit

被引：0
|
作者：
K Min
NN Kim
I McAuley
M Stankowicz
I Goldstein
AM Traish
机构：
[1] Boston University School of Medicine,Departments of Urology
[2] Obstetrics/Gynecology,undefined
[3] Boston University School of Medicine,undefined
来源：
International Journal of Impotence Research | 2000年 / 12卷
关键词：
female genital sexual arousal; vaginal and clitoral blood flow; vaginal lubrication; sildenafil;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The NO‐cGMP pathway has been implicated in clitoral and vaginal smooth muscle relaxation based on previous immunochemical, biochemical and physiologic studies. There are limited data from in vivo studies demonstrating enhancement of the genital sexual arousal response by pharmacologic agents influencing the NO‐cGMP pathway. The goal of this study was to investigate if sildenafil, a phosphodiesterase type‐5 inhibitor, facilitated female genital sexual arousal in an animal model in response to pelvic nerve stimulation (PNS).
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页码：S32 / S39
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