Larvicidal activity of Ramalina usnea lichen against Aedes aegypti

被引：0
|
作者：
Antônio S. N. Moreira
Roberta O. S. Fernandes
Francisco J. A. Lemos
Raimundo Braz-Filho
Ivo J. C. Vieirae
机构：
[1] Universidade Estadual do Norte Fluminense Darcy Ribeiro,Programa de Pós
[2] Instituto Federal Fluminense,graduação em Ciências Naturais
[3] Campus Guarus,Departamento de Farmácia
[4] Faculdade de Medicina de Campos,Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia
[5] Universidade Estadual do Norte Fluminense Darcy Ribeiro,Laboratório de Ciências Químicas, Centro de Ciência e Tecnologia
[6] Universidade Estadual do Norte Fluminense Darcy Ribeiro,undefined
来源：
Revista Brasileira de Farmacognosia | 2016年 / 26卷
关键词：
Larvicidal activity; Lichenized fungi; Ramalina usnea;
D O I：
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中图分类号：
学科分类号：
摘要：
The larvicidal activity of the methanol extract, fractions and compounds 2-hydroxy-4-methoxy-6-propyl-methyl benzoate and (+)-usnic acid identified from the lichen Ramalina usnea (L) R. Howe. Ramalinaceae. was tested against the third instar larvae of the Aedes aegypti mosquito. The methanol extract and three fractions showed activity, killing 100% and 96.6% of the larvae at a concentration of 150fig/ml at 24 h. The isolated compounds. 2-hydroxy-4-methoxy-6-propyl-methyl benzoate and the (+)-usnic acid showed larvicidal activity, presenting LC50 values of 4.85 and 4.48u.g/ml. respectively. This is the first study of its kind reporting the larvicidal activity against the A. aegypti mosquito with compound (1).
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页码：530 / 532
页数：2
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