Thermodynamic Unfolding and Aggregation Fingerprints of Monoclonal Antibodies Using Thermal Profiling

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作者：
Richard Melien
Patrick Garidel
Dariush Hinderberger
Michaela Blech
机构：
[1] Martin-Luther-Universität Halle-Wittenberg,Institute of Chemistry
[2] Boehringer Ingelheim Pharma GmbH & Co. KG,Pharmaceutical Development Biologicals
来源：
Pharmaceutical Research | 2020年 / 37卷
关键词：
antibody; Differential Scanning Calorimetry (DSC); Intrinsic Fluorescence (IF) spectroscopy; protein aggregation; thermal stability; thermodynamics; unfolding;
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