Synthesis and biological activity of the 2-amino-4-(4-iodophenyl)amino-6-methylpyrimidine isosteric analogs

被引：0
|
作者：
A. V. Erkin
V. I. Krutikov
机构：
[1] St. Petersburg State Institute of Technology (Technical University),
来源：
Russian Journal of General Chemistry | 2013年 / 83卷
关键词：
Halogen Atom; Hydrogen Chloride; Mycobacterium Smegmatis; Phosphorus Oxychloride; Aqueous Potassium Hydroxide;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Transformation of the structure of 6-methylisocytosine results in the isosteric analogs of 2-amino-4-(4-iodophenyl)amino-6-methylpyrimidine exhibiting tuberculocidal properties. The level of biological activity of the synthesized compounds depends on the site of location of the halogen atom.
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收藏
页码：538 / 541
页数：3
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