Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

被引：0
|
作者：
Dmitry Usoskin
Alessandro Furlan
Saiful Islam
Hind Abdo
Peter Lönnerberg
Daohua Lou
Jens Hjerling-Leffler
Jesper Haeggström
Olga Kharchenko
Peter V Kharchenko
Sten Linnarsson
Patrik Ernfors
机构：
[1] Karolinska Institutet,Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics
[2] Karolinska Institutet,Division of Physiological Chemistry, Department of Medical Biochemistry and Biophysics
[3] Center for Biomedical Informatics,Division of Hematology/Oncology
[4] Harvard Medical School,undefined
[5] Children's Hospital,undefined
来源：
Nature Neuroscience | 2015年 / 18卷
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摘要：
Based on single cell RNA-sequencing of 622 adult mouse sensory neurons, Usoskin et al. performed unbiased classification to identify the cellular and molecular complexity underlying somatic sensation. Eleven different subtypes were identified, including some previously unknown populations such as a new class of neuron which may be sensitive to inflammatory itch.
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页码：145 / 153
页数：8
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