Tryptophan-kynurenine profile in pediatric autoimmune hepatitis

被引：0

作者：

Simon D. Lytton

Marcin Osiecki

Bożena MałgorzataWoźniak

Aldona Cukrowska

Maria Wierzbicka

Piotr Goliszek

Wojciech Socha

Dilek Janczyk

Dieter Dayanakli

Sabine Abendroth

Kai Kramp

Thomas Fechner

Michael Scheper

Chelsea Mahler

Dimietrios Bentow

Dietmar Bogdanos

Marek Fuchs

机构：

[1] SeraDiaLogistics,Division of Biological Chemistry, Biocenter Innsbruck Medical University

[2] Children’s Memorial Health Institute,Department of Rheumatology and Clinical Immunology, University General Hospital of Larissa, Faculty of Medicine, School of Health Sciences

[3] Zentrum für Chirurgie Universitätsklinikum Universität Ulm,undefined

[4] Center for Chemistry and Biomedicine,undefined

[5] Euroimmun AG,undefined

[6] University of Thessaly,undefined

[7] Inova Diagnostics,undefined

来源：

Immunologic Research | 2019年 / 67卷

关键词：

Pediatric autoimmune hepatitis; Autoantibodies; Tryptophan; Kynurenine; Treg cells; Serum IDO activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The impairment of regulatory T cells (Tregs) is a characteristic feature of autoimmune hepatitis (AIH), and the degradation of tryptophan (Trp) to kynurenine (Kyn), by gamma interferon-induced indoleamine-2,3-dioxygenase-1 (IDO-1), is a central metabolomics check point in the differentiation of Tregs. For this reason, we investigate whether or not Kyn and IDO activity is potentially useful biomarkers in pediatric AIH.

引用

页码：39 / 47

页数：8

共 50 条

[1] Tryptophan-kynurenine profile in pediatric autoimmune hepatitis
Lytton, Simon D.
Osiecki, Marcin
MalgorzataWozniak
Cukrowska, Bozena
Wierzbicka, Aldona
Goliszek, Maria
Socha, Piotr
Janczyk, Wojciech
Dayanakli, Dilek
Abendroth, Dieter
Kramp, Sabine
Fechner, Kai
Scheper, Thomas
Mahler, Michael
Bentow, Chelsea
Bogdanos, Dimietrios
Fuchs, Dietmar
Woynarowski, Marek
[J]. IMMUNOLOGIC RESEARCH, 2019, 67 (01) : 39 - 47
[2] Tryptophan-kynurenine metabolism in migraine patients
Majlath, Z.
Veres, G.
Zadori, D.
Balog, A.
Watti, N.
Tajti, J.
Vecsei, L.
[J]. JOURNAL OF HEADACHE AND PAIN, 2014, 15
[3] The Tryptophan-Kynurenine pathway in the control of energy metabolism
Ruas, Jorge Lira
[J]. ANNALS OF NUTRITION AND METABOLISM, 2023, 79 : 85 - 85
[4] Tryptophan-kynurenine ratio as a biomarker of bladder cancer
Lee, Sze Han
Mahendran, Ratha
Tham, Sin Mun
Thamboo, Thomas Paulraj
Chionh, Billy Jianhao
Lim, Yi Xin
Tsang, Woon Chau
Wu, Qing Hui
Chia, Jun Yang
Tay, Melissa Hui Wen
Goh, Benjamin Yen Seow
Chen, Kelven Weijing
Mallari, Jeane Zepeda
Periaswami, Revathi
Raman, Lata
Choo, Shoa Nian
Kioh, Dorinda Yan Qin
Chiong, Edmund
Esuvaranathan, Kesavan
Chan, Eric Chun Yong
[J]. BJU INTERNATIONAL, 2021, 127 (04) : 445 - 453
[5] The tryptophan-kynurenine pathway in immunomodulation and cancer metastasis
Basson, Charlise
Serem, June Cheptoo
Hlophe, Yvette Nkondo
Bipath, Priyesh
[J]. CANCER MEDICINE, 2023, 12 (18): : 18691 - 18701
[6] ACCUMULATION OF TRYPTOPHAN-KYNURENINE METABOLITES IN THE KIDNEY IN DIABETIC NEPHROPATHY
Ishimine, Hisako
Umeda, Ryosuke
Matsushita, Shoko
Yoshimura, Aya
Ohyama, Yukako
Fukasawa, Motoaki
Nakajima, Kazuki
Fujigaki, Hidetsugu
Yamamoto, Yasuko
Mouri, Akihiro
Nabeshima, Toshitaka
Setou, Mitsutoshi
Saito, Kuniaki
Tsuboi, Naotake
Yuzawa, Yukio
Takahashi, Kazuo
[J]. NEPHROLOGY, 2020, 25 : 57 - 57
[7] The Impact of Electroconvulsive Therapy on the Tryptophan-Kynurenine Metabolic Pathway
Guloksuz, Sinan
Arts, Baer
Walter, Sharon
Drukker, Marjan
Myint, Aye-Mu
Ponds, Rudolf
van Os, Jim
Kenis, Gunter
Rutten, Bart P. F.
[J]. BIOLOGICAL PSYCHIATRY, 2014, 75 (09) : 122S - 122S
[8] Tryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation
Wang, Qiongxin
Liu, Danxia
Song, Ping
Zou, Ming-Hui
[J]. FRONTIERS IN BIOSCIENCE-LANDMARK, 2015, 20 : 1116 - 1143
[9] The impact of electroconvulsive therapy on the tryptophan-kynurenine metabolic pathway
Guloksuz, Sinan
Arts, Baer
Walter, Sharon
Drukker, Marjan
Rodriguez, Laura
Myint, Aye-Mu
Schwarz, Markus J.
Ponds, Rudolf
van Os, Jim
Kenis, Gunter
Rutten, Bart P. F.
[J]. BRAIN BEHAVIOR AND IMMUNITY, 2015, 48 : 48 - 52
[10] ROLE OF TRYPTOPHAN-KYNURENINE PATHWAY IN DEPRESSION: PSYCHOPATHOLOGICAL ASPECT
Myint, A. -M.
[J]. EUROPEAN PSYCHIATRY, 2009, 24

← 1 2 3 4 5 →