Synthesis of spiro[imidazo[2,1-b][1,3]thiazole-6,3'-pyrrolidine] derivatives

被引：0
|
作者：
Lesya M. Saliyeva
Nataliia Yu. Slyvka
Dmitro A. Mel’nyk
Eduard B. Rusanov
Ruslan I. Vas’kevich
Mikhailo V. Vovk
机构：
[1] Lesya Ukrainka East European National University,
[2] Ivano-Frankivsk National Medical University,undefined
[3] Institute of Organic Chemistry,undefined
[4] National Academy of Sciences of Ukraine,undefined
来源：
Chemistry of Heterocyclic Compounds | 2018年 / 54卷
关键词：
6-arylideneimidazo[2,1-; ][1,3]thiazoles; azomethine ylides; spiro[imidazo[2,1-; ][1,3]thiazole-6,3'-pyrrolidines]; [2+3] cycloaddition;
D O I：
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学科分类号：
摘要：
6-Arylidene-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5(6Н)-ones reacted with N-alkylazomethine ylides by [2+3] cycloaddition mechanism, resulting in the formation of diastereomeric spiro[imidazo[2,1-b][1,3]thiazole-6,3'-pyrrolidin]-5(6Н)-ones, which were separated by column chromatography.
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页码：130 / 137
页数：7
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