Effects of Music Therapy Combined with Progressive Muscle Relaxation on Anxiety and Depression Symptoms in Adult Women with Methamphetamine Dependence: Study Protocol for a Randomized Controlled Trail

This study attempted to assess the influence of music therapy combined with progressive muscle relaxation on relieving anxiety and depression symptoms in methamphetamine-dependent adult women. It was a randomized controlled trial including 133 methamphetamine-dependent adult women recruited to participate in an 8-week rehabilitation program in the rehabilitation center of a psychiatric hospital. Participants in the control group were only treated by routine medical care, while participants in the study group received music therapy combined with progressive muscle relaxation based on routine medical care. Demographic and clinical data of these participants were collected at baseline, and anxiety and depression scores were collected at baseline and after 8 weeks intervention. Seven participants left halfway of the study, and the final available data in the study group and the control group were both 63. After 8-week intervention, anxiety and depression scores in the study group were less than those of the control group (p < 0.001). In addition, the decline of anxiety and depression scores after 8 weeks intervention in the study group was more than those in the control group (p < 0.001). These findings recommended that the music therapy combined with progressive muscle relaxation would be considered as a safe, noninvasive, and effective rehabilitation therapy for adult women with methamphetamine dependence. Trial registration number: ChiCTR-ROC-15006327. Date of registration: 2015/03/20.