A Case Control Study on the Contribution of Factor V-Leiden, Prothrombin G20210A, and MTHFR C677T Mutations to the Genetic Susceptibility of Deep Venous Thrombosis

被引：0
|
作者：
Wassim Y. Almawi
Hala Tamim
Raghid Kreidy
Georgina Timson
Elias Rahal
Malak Nabulsi
Ramzi R. Finan
Noha Irani-Hakime
机构：
[1] Arabian Gulf University,Al
[2] American University of Beirut,Jawhara Center for Molecular Medicine, Genetics, and Inherited Diseases
[3] St. Georges University Hospital,Faculty of Health Sciences
[4] Islamic Hospital,Al
[5] Arabian Gulf University,Jawhara Center for Molecular Medicine, Genetics and Inherited Diseases
来源：
Journal of Thrombosis and Thrombolysis | 2005年 / 19卷
关键词：
Venous Thrombosis; Factor V-Leiden; Prothrombin G20210A; MTHFR C677T; PCR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Insofar as the inherited prothrombotic single nucleotide polymorphisms (SNPs) factor V G1691A (FV-Leiden), prothrombin (PRT) G20210A, and methylenetetrahydrofolate reductase (MTHFR), C677T are inherited risk factors of venous thromboembolism (VTE), the aim of this study was to determine the prevalence of single and combined SNPs in 198 patients with documented deep venous thrombosis (DVT), and 697 control subjects, and to estimate the associated risks.
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页码：189 / 196
页数：7
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