A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

被引：0

作者：

Lars Kuepfer

Olivia Clayton

Christoph Thiel

Henrik Cordes

Ramona Nudischer

Lars M. Blank

Vanessa Baier

Stephane Heymans

Florian Caiment

Adrian Roth

David A. Fluri

Jens M. Kelm

José Castell

Nathalie Selevsek

Ralph Schlapbach

Hector Keun

James Hynes

Ugis Sarkans

Hans Gmuender

Ralf Herwig

Steven Niederer

Johannes Schuchhardt

Matthew Segall

Jos Kleinjans

机构：

[1] Institute of Applied Microbiology,Roche Pharmaceutical Research and Early Development

[2] Roche Innovation Center Basel,Department of Cardiology

[3] Cardiovascular Research Institute Maastricht,Department of Cardiovascular Sciences

[4] Maastricht University,Department of Toxicogenomics

[5] Leuven University,Functional Genomics Center Zurich

[6] Maastricht University,Division of Cancer, Department of Surgery and Cancer

[7] InSphero AG,Department Computational Molecular Biology

[8] Instituto de Investigación Sanitaria. Hospital Universitario La Fe,Department of Imaging Sciences and BioMedical Engineering

[9] ETH Zurich and University of Zurich,undefined

[10] Imperial College London,undefined

[11] Luxcel Biosciences Ltd,undefined

[12] European Molecular Biology Laboratory,undefined

[13] Genedata AG,undefined

[14] Max-Planck-Institute for Molecular Genetics,undefined

[15] King’s College London,undefined

[16] Microdiscovery GmbH,undefined

[17] Optibrium Ltd,undefined

来源：

Archives of Toxicology | 2018年 / 92卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

引用

页码：553 / 555

页数：2

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