Epigenetic control of polyamines by the prion [PSI+]

被引:0
|
作者
Olivier Namy
Aurélie Galopier
Cyrielle Martini
Senya Matsufuji
Céline Fabret
Jean-Pierre Rousset
机构
[1] IGM,Department of Molecular Biology
[2] CNRS,undefined
[3] UMR 8621,undefined
[4] Univ Paris-Sud,undefined
[5] The Jikei University School of Medicine,undefined
来源
Nature Cell Biology | 2008年 / 10卷
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摘要
Namy et al. show that the yeast prion form of the eERF3 translation termination factor boosts antizyme expression, which reduces polyamine synthesis. Changes in polyamine levels account for most of the phenotypic traits conferred by this prion.
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页码:1069 / 1075
页数:6
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