Clonal haematopoiesis and atherosclerosis: a chicken or egg question?

被引：0
|
作者：
Fátima Sánchez-Cabo
José J. Fuster
机构：
[1] Centro Nacional de Investigaciones Cardiovasculares (CNIC),
来源：
Nature Reviews Cardiology | 2021年 / 18卷
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摘要：
Sequencing studies demonstrate a strong clinical association between clonal haematopoiesis driven by acquired mutations and atherosclerotic disease. Previous research supports the idea that this association reflects a direct contribution of some clonal haematopoiesis-related mutations to atherosclerosis. Now, mathematical modelling suggests that atherosclerosis could instead accelerate clonal haematopoiesis.
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页码：463 / 464
页数：1
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