Why novel mRNA modifications are so challenging and what we can do about it

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作者
Audrey Penning
Jana Jeschke
François Fuks
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[1] Université libre de Bruxelles,Laboratory of Cancer Epigenetics, Faculty of Medicine, ULB
[2] Institut Jules Bordet,Cancer Research Centre (U
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The discovery of diverse chemical modifications of mRNA has spurred efforts to identify, map and characterize them. Yet aside from N6-methyladenosine (m6A), progress in epitranscriptomics has been stymied by discrepant data. Here we discuss the main obstacles in studying novel mRNA modifications and offer insights into how to surmount them.
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页码:385 / 386
页数:1
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