Evaluation of a multi-layer microbraided polylactic acid fiber-reinforced conduit for peripheral nerve regeneration

被引：0

作者：

Ming-Chin Lu

Yen-Ting Huang

Jia-Horng Lin

Chun-Hsu Yao

Ching-Wen Lou

Chin-Chuan Tsai

Yueh-Sheng Chen

机构：

[1] China Medical University,School of Post Baccalaureate Chinese Medicine

[2] China Medical University,Laboratory of Biomaterials, Graduate Institute of Chinese Medical Science

[3] Feng Chia University,Laboratory of Fiber Application and Manufacturing, Graduated Institute of Textile Engineering

[4] Central Taiwan University of Science and Technology,Institute of Biomedical Engineering and Material Science

[5] I-Su University,Department of Biological Science & Technology

来源：

Journal of Materials Science: Materials in Medicine | 2009年 / 20卷

关键词：

Sciatic Nerve; Polylactic Acid; Nerve Conductive Velocity; Peripheral Nerve Regeneration; Nerve Stump;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We evaluated peripheral nerve regeneration using a biodegradable multi-layer microbraided polylactic acid (PLA) fiber-reinforced conduit. Biodegradability of the PLA conduit and its effectiveness as a guidance channel were examined as it was used to repair a 10 mm gap in the rat sciatic nerve. As a result, tube fragmentation was not obvious and successful regeneration through the gap occurred in all the conduits at 8 weeks after operation. These results indicate the superiority of the PLA materials and suggest that the multi-layer microbraided PLA fiber-reinforced conduits provide a promising tool for neuro-regeneration.

引用

页码：1175 / 1180

页数：5

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