Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

被引：0
|
作者：
Jia Zhu
Tao Peng
Christine Johnston
Khamsone Phasouk
Angela S. Kask
Alexis Klock
Lei Jin
Kurt Diem
David M. Koelle
Anna Wald
Harlan Robins
Lawrence Corey
机构：
[1] University of Washington,Department of Laboratory Medicine
[2] Fred Hutchinson Cancer Research Center,Vaccine and Infectious Disease Division
[3] University of Washington,Department of Medicine
[4] University of Washington,Department of Pathobiology
[5] Benaroya Research Institute,Department of Epidemiology
[6] University of Washington,undefined
[7] Program in Computational Biology,undefined
[8] Fred Hutchinson Cancer Research Center,undefined
来源：
Nature | 2013年 / 497卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Herpes simplex virus 2-infected individuals are shown to have skin-tissue-resident CD8αα+ T cells that persist at the portal of virus release in genital skin and mucosa, possess oligoclonal T-cell-receptor-β CDR3 sequences that are stable over time, and express gene signatures of antiviral and cytolytic function indicative of viral-specific immune surveillance.
引用
收藏
页码：494 / 497
页数：3
相关论文
共 50 条
  • [1] Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection
    Zhu, Jia
    Peng, Tao
    Johnston, Christine
    Phasouk, Khamsone
    Kask, Angela S.
    Klock, Alexis
    Jin, Lei
    Diem, Kurt
    Koelle, David M.
    Wald, Anna
    Robins, Harlan
    Corey, Lawrence
    [J]. NATURE, 2013, 497 (7450) : 494 - +
  • [2] Correction: Corrigendum: Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection
    Jia Zhu
    Tao Peng
    Christine Johnston
    Khamsone Phasouk
    Angela S. Kask
    Alexis Klock
    Lei Jin
    Kurt Diem
    David M. Koelle
    Anna Wald
    Harlan Robins
    Lawrence Corey
    [J]. Nature, 2013, 500 : 242 - 242
  • [3] Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection (vol 497, pg 494, 2013)
    Zhu, Jia
    Peng, Tao
    Johnston, Christine
    Phasouk, Khamsone
    Kask, Angela S.
    Klock, Alexis
    Jin, Lei
    Diem, Kurt
    Koelle, David M.
    Wald, Anna
    Robins, Harlan
    Corey, Lawrence
    [J]. NATURE, 2013, 500 (7461) : 242 - 242
  • [4] Human tissue-resident memory T cells Skin-resident memory T cells keep herpes simplex virus at bay
    Gebhardt, Thomas
    Mackay, Laura K.
    [J]. IMMUNOLOGY AND CELL BIOLOGY, 2013, 91 (07): : 441 - 442
  • [5] Skin-resident memory T cells and melanoma surveillance
    Park, S.
    Buzzai, A.
    Hochheiser, K.
    Rautela, J.
    Hor, J. L.
    Effern, M.
    McBain, N.
    Whitney, P.
    Mueller, S.
    Huntington, N.
    Tuting, T.
    Herold, M.
    Holzel, M.
    Bedoui, S.
    Mackay, L.
    Waithman, J.
    Gebhardt, T.
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 2017, 47 : 8 - 8
  • [6] Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells
    Vella, Jennifer L.
    Molodtsov, Aleksey
    Angeles, Christina, V
    Branchini, Bruce R.
    Turk, Mary Jo
    Huang, Yina H.
    [J]. LIFE SCIENCE ALLIANCE, 2021, 4 (10)
  • [7] Functions of skin-resident γδ T cells
    MacLeod, Amanda S.
    Havran, Wendy L.
    [J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2011, 68 (14) : 2399 - 2408
  • [8] Functions of skin-resident γδ T cells
    Amanda S. MacLeod
    Wendy L. Havran
    [J]. Cellular and Molecular Life Sciences, 2011, 68 : 2399 - 2408
  • [9] CD8 T-CELLS IN HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION
    STRICKER, RB
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1993, 153 (06) : 779 - 779
  • [10] An early expansion of CD8αβ T cells, but depletion of resident CD8αα T cells, occurs in the intestinal epithelium during primary simian immunodeficiency virus infection
    Mattapallil, JJ
    Reay, E
    Dandekar, S
    [J]. AIDS, 2000, 14 (06) : 637 - 646
12345