The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques

被引：0
|
作者：
Janine M van Gils
Merran C Derby
Luciana R Fernandes
Bhama Ramkhelawon
Tathagat D Ray
Katey J Rayner
Sajesh Parathath
Emilie Distel
Jessica L Feig
Jacqueline I Alvarez-Leite
Alistair J Rayner
Thomas O McDonald
Kevin D O'Brien
Lynda M Stuart
Edward A Fisher
Adam Lacy-Hulbert
Kathryn J Moore
机构：
[1] Marc and Ruti Bell Vascular Biology and Disease Program,Leon H. Charney Division of Cardiology, Department of Medicine
[2] New York University School of Medicine,Department of Medicine
[3] Massachusetts General Hospital,Department of Biochemistry and Immunology
[4] Harvard Medical School,Division of Cardiology
[5] Federal University of Minas Gerais,Department of Pediatrics
[6] Belo Horizonte –,Department of Cell Biology
[7] University of Washington,undefined
[8] Program for Developmental Immunology,undefined
[9] Massachusetts General Hospital,undefined
[10] Harvard Medical School,undefined
[11] New York University School of Medicine,undefined
来源：
Nature Immunology | 2012年 / 13卷
关键词：
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学科分类号：
摘要：
Lipid-engorged macrophages accumulate in atherosclerotic plaques where chronic inflammation ensues. Moore and colleagues show that macrophage migration to chemokines and egress is arrested by netrin-1, which is secreted in the plaque lesions.
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页码：136 / 143
页数：7
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