Role of Dendritic Cells in the Formation of Subpopulation of Cytotoxic T-Lymphocytes in the Thymus during Its Aging

被引：0
|
作者：
N. S. Linkova
V. O. Polyakova
I. M. Kvetnoy
机构：
[1] the North Western Division of the Russian Academy of Medical Sciences,St. Petersburg Institute of Bioregulation and Gerontology
来源：
Bulletin of Experimental Biology and Medicine | 2011年 / 151卷
关键词：
dendritic cells; cytotoxic T-lymphocytes; thymus; aging;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The counts of dendritic cells and cytotoxic T-lymphocytes in the thymus decrease during its aging. The counts of dendritic cells decrease in senile age, while low counts of cytotoxic T-cells are observed only in long-living individuals. Presumably, reduction of the counts of thymic dendritic cells causes disorders in the differentiation of T-cells, particularly of cytotoxic ones, which can represent a mechanism of thymus involution during its aging.
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页码：457 / 459
页数：2
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