Silent synapses and the emergence of a postsynaptic mechanism for LTP

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作者
Geoffrey A. Kerchner
Roger A. Nicoll
机构
[1] University of California,Department of Cellular and Molecular Pharmacology
[2] San Francisco,Department of Neurology
[3] University of California,Department of Physiology
[4] San Francisco,undefined
[5] University of California,undefined
[6] San Francisco,undefined
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摘要
Silent synapses cannot mediate neurotransmission. Kerchner and Nicoll discuss different mechanisms that have been proposed to underlie synaptic silence, and conclude that LTP and synaptic unsilencing occur by a postsynaptic mechanism that involves AMPA receptor recruitment.
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页码:813 / 825
页数:12
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