A Description of the Clinical Characteristics at Baseline of Patients Recruited into the Carvedilol or Metoprolol European Trial (COMET)

被引：0
|
作者：
John G.F. Cleland
Kevin Goode
Leif Erhardt
Willem J. Remme
Andrew Charlesworth
Philip A. Poole-Wilson
Andrea Di Lenarda
Peter Hanrath
Michel Komajda
Marco Metra
Karl Swedberg
Christian Torp-Pedersen
机构：
[1] University of Hull,
[2] Malmö University Hospital,undefined
[3] Sticares Cardiovascular Research Foundation,undefined
[4] Nottingham Clinical Research Group,undefined
[5] National Heart and Lung Institute,undefined
[6] Ospedale Di Cattinara,undefined
[7] University Hospital,undefined
[8] La Pitié-Salpétrière Hospital,undefined
[9] Università di Brescia,undefined
[10] Sahlgrenska University Hospital/Östra,undefined
[11] Bispebjerg University Hospital,undefined
来源：
Cardiovascular Drugs and Therapy | 2004年 / 18卷
关键词：
heart failure; carvedilol; metoprolol;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background & Aims: The COMET trial was a prospective, double-blind, randomised trial comparing carvedilol, a comprehensive adrenergic receptor antagonist, with metoprolol, a beta-1-selective agent in patients with heart failure and left ventricular systolic dysfunction. The trial showed a reduction in mortality with carvedilol that was consistent across subgroups. The purpose of this report is to describe in greater detail the heterogeneity of this population at baseline with particular reference to the impact of symptomatic severity, age and gender on patient characteristics.
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页码：139 / 152
页数：13
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