T cells of the immune system develop through a lineage-commitment step followed by two checkpoints. The finding that the first checkpoint is needed to complete commitment offers a fresh perspective on T-cell development.
机构:
Univ Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal
Univ Lisbon, Inst Super Tecn, P-1649028 Lisbon, PortugalUniv Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal
Di Lorenzo, Biagio
Dechanet-Merville, Julie
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Univ Bordeaux, Equipe Labelisee Ligue Canc, CNRS, ImmunoConcept,UMR 5164, F-33000 Bordeaux, FranceUniv Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal
Dechanet-Merville, Julie
Silva-Santos, Bruno
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Univ Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, PortugalUniv Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal
机构:
Ctr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, GreeceCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Vardi, Anna
Agathangelidis, Andreas
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Ist Sci San Raffaele, Div Mol Oncol, Milan, Italy
Ist Sci San Raffaele, Dept Oncohematol, Milan, Italy
Fdn Ctr San Raffaele, Milan, ItalyCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Agathangelidis, Andreas
Stalika, Evangelia
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Ctr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, GreeceCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Stalika, Evangelia
Karypidou, Maria
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机构:
Ctr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
G Papanicolaou Hosp, Dept Hematol, Thessaloniki, Greece
G Papanicolaou Hosp, HCT Unit, Thessaloniki, GreeceCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Karypidou, Maria
Siorenta, Alexandra
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机构:
Gen Hosp Athens G Gennimatas, Immunol, Athens, Greece
Gen Hosp Athens G Gennimatas, Natl Tissue Typing Ctr, Athens, GreeceCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Siorenta, Alexandra
Anagnostopoulos, Achilles
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机构:
G Papanicolaou Hosp, Dept Hematol, Thessaloniki, Greece
G Papanicolaou Hosp, HCT Unit, Thessaloniki, GreeceCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Anagnostopoulos, Achilles
Rosenquist, Richard
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机构:
Uppsala Univ, Dept Immunol Genet & Pathol, Sci Life Lab, SE-75185 Uppsala, SwedenCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Rosenquist, Richard
Hadzidimitriou, Anastasia
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Ctr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, GreeceCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Hadzidimitriou, Anastasia
Ghia, Paolo
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机构:
Ist Sci San Raffaele, Div Mol Oncol, Milan, Italy
Ist Sci San Raffaele, Dept Oncohematol, Milan, Italy
Fdn Ctr San Raffaele, Milan, ItalyCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Ghia, Paolo
Sutton, Lesley-Ann
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机构:
Uppsala Univ, Dept Immunol Genet & Pathol, Sci Life Lab, SE-75185 Uppsala, SwedenCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
Sutton, Lesley-Ann
Stamatopoulos, Kostas
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机构:
Ctr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece
G Papanicolaou Hosp, Dept Hematol, Thessaloniki, Greece
G Papanicolaou Hosp, HCT Unit, Thessaloniki, Greece
Uppsala Univ, Dept Immunol Genet & Pathol, Sci Life Lab, SE-75185 Uppsala, SwedenCtr Res & Technol Hellas, Inst Appl Biosci, Thessaloniki, Greece