Preclinical characterization and anti-SARS-CoV-2 efficacy of ATV014: an oral cyclohexanecarboxylate prodrug of 1′-CN-4-aza-7,9-dideazaadenosine C-nucleoside

被引：0

作者：

Qifan Zhou

Sidi Yang

Liu Cao

Yang Yang

Tiefeng Xu

Qishu Chen

Hongzhou Lu

Yingjun Li

Deyin Guo

Xumu Zhang

机构：

[1] Southern University of Science and Technology,Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Academy for Advanced Interdisciplinary Studies and Medi

[2] Shenzhen Campus of Sun Yat-sen University,X Pingshan

[3] Guangzhou Laboratory,Centre for Infection and Immunity Studies (CIIS), School of Medicine

[4] Bio-Island,Shenzhen Key Laboratory of Pathogen and Immunity, National Clinical Research Center for infectious disease, State Key Discipline of Infectious Disease, Shenzhen Third People′s Hospital

[5] Second Hospital Affiliated to Southern University of Science and Technology,undefined

来源：

Signal Transduction and Targeted Therapy | / 8卷

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共 2 条

[1] Preclinical characterization and anti-SARS-CoV-2 efficacy of ATV014: an oral cyclohexanecarboxylate prodrug of 1′-CN-4-aza-7,9-dideazaadenosine C-nucleoside
Zhou, Qifan
Yang, Sidi
Cao, Liu
Yang, Yang
Xu, Tiefeng
Chen, Qishu
Lu, Hongzhou
Li, Yingjun
Guo, Deyin
Zhang, Xumu
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 8 (01)
[2] Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV
Mackman, Richard L.
Hui, Hon C.
Perron, Michel
Murakami, Eisuke
Palmiotti, Christopher
Lee, Gary
Stray, Kirsten
Zhang, Lijun
Goyal, Bindu
Chun, Kwon
Byun, Daniel
Siegel, Dustin
Simonovich, Scott
Du Pont, Venice
Pitts, Jared
Babusis, Darius
Vijjapurapu, Arya
Lu, Xianghan
Kim, Cynthia
Zhao, Xiaofeng
Chan, Julie
Ma, Bin
Lye, Diane
Vandersteen, Adelle
Wortman, Sarah
Barrett, Kimberly T.
Toteva, Maria
Jordan, Robert
Subramanian, Raju
Bilello, John P.
Cihlar, Tomas
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (08) : 5001 - 5017

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