Role of tumor cells contaminating the graft in breast cancer recurrence after high-dose chemotherapy

被引：0
|
作者：
P Pedrazzoli
M Battaglia
GADa Prada
A Lanza
A Cuomo
F Bertolini
L Pavesi
G Robustelli della Cuna
机构：
[1] IRCCS ‘Salvatore Maugeri’ Foundation,Division of Medical Oncology
[2] Rehabilitation Institute of Pavia,undefined
来源：
Bone Marrow Transplantation | 1997年 / 20卷
关键词：
metastatic breast cancer; PBPC transplantation; tumor recurrence;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
One of the possible drawbacks to autologous stem cell transplantation in breast cancer (BC) patients is the potential for tumor contamination in the transplanted product. We present a patient with advanced disease who received high-dose chemotherapy (HDC) and PBPC support as consolidation therapy after achieving complete remission with standard-dose first-line treatment, and suffered recurrence of the disease 6 months after transplantation. Retrospective analysis revealed the presence of contaminating cells in the leukapheretic product, and clinical evidence suggested a role for these cells in the tumor relapse.
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页码：167 / 169
页数：2
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