Simultaneous analysis of acephate and methamidophos in human serum by improved extraction and GC-MS

被引：0
|
作者：
Nobuyuki Adachi
Hiroshi Kinoshita
Minori Nishiguchi
Motonori Takahashi
Harumi Ouchi
Takako Minami
Kiyoshi Matsui
Takehiko Yamamura
Hiroyuki Motomura
Nao Ohtsu
Shie Yoshida
Shigeru Hishida
机构：
[1] Hyogo College of Medicine,Department of Legal Medicine
[2] Hyogo College of Medicine,Joint
[3] Forensic Science Laboratory,Use Research Facilities
[4] Hyogo Prefectural Police Headquarters,undefined
来源：
Forensic Toxicology | 2008年 / 26卷
关键词：
Acephate; Methamidophos; Fenitrothion; Activated charcoal cartridge; GC-MS; Serum sample;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A detailed procedure for simple and rapid analysis of acephate, an organophosphorous pesticide, and its metabolite methamidophos in human serum by gas chromatography-mass spectrometry was established. The method included solid-phase extraction with activated charcoal, which gave high recoveries of both analytes. After validation of the method, it was successfully applied to a serum sample obtained from an actual poisoning case. The present method seems very useful, especially in forensic and environmental toxicology.
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