Rotavirus vaccines: Current controversies and future directions

被引:4
|
作者
Coffin S.E. [1 ]
机构
[1] Division of Immunologic and Infectious Diseases, The Children’s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, 19104, PA
关键词
Intussusception; Reassortant Vaccine; Vaccine Adverse Event Reporting System;
D O I
10.1007/s11908-000-0090-0
中图分类号
学科分类号
摘要
Rotaviruses are the most important cause of pediatric gastroenteritis worldwide. In August 1998, a new rotavirus vaccine was licensed for general use in the United States. However, 14 months later, the vaccine was withdrawn from the market because of serious gastrointestinal side effects. This paper discusses the need for a rotavirus vaccine, the development of the first rotavirus vaccine, and the safety issues that led to the recall of that vaccine. © 2000, Current Science Inc.
引用
收藏
页码:68 / 72
页数:4
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