Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100

被引：0
|
作者：
Piotr Maczuga
Annemart Koornneef
Florie Borel
Harald Petry
Sander van Deventer
Tita Ritsema
Pavlina Konstantinova
机构：
[1] uniQure biopharma b.v.,Department of Research & Development
[2] Leiden University Medical Center,Department of Gastroenterology and Hepatology
[3] Academic Medical Center,Department of Gastroenterology and Hepatology
来源：
BMC Biotechnology | / 12卷
关键词：
Transcription Start Site; Stem Length; shRNA Expression; Guide Strand; siRNA Molecule;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 4 条
  • [1] Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100
    Maczuga, Piotr
    Koornneef, Annemart
    Borel, Florie
    Petry, Harald
    van Deventer, Sander
    Ritsema, Tita
    Konstantinova, Pavlina
    BMC BIOTECHNOLOGY, 2012, 12
  • [2] Embedding siRNA sequences targeting Apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy
    Maczuga, Piotr
    Lubelski, Jacek
    van Logtenstein, Richard
    Borel, Florie
    Blits, Bas
    Fakkert, Erwin
    Costessi, Adalberto
    Butler, Derek
    van Deventer, Sander
    Petry, Harald
    Koornneef, Annemart
    Konstantinova, Pavlina
    HUMAN GENE THERAPY, 2012, 23 (10) : A77 - A77
  • [3] Embedding siRNA sequences targeting Apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy
    Maczuga, Piotr
    Lubelski, Jacek
    van Logtenstein, Richard
    Borel, Florie
    Blits, Bas
    Fakkert, Erwin
    Costessi, Adalberto
    Butler, Derek
    van Deventer, Sander
    Petry, Harald
    Koornneef, Annemart
    Konstantinova, Pavlina
    MOLECULAR THERAPY, 2013, 21 (01) : 217 - 227
  • [4] Comparison of apolipoprotein B100 metabolism between continuous subcutaneous and intraperitoneal insulin therapy in type 1 diabetes
    Duvillard, L
    Florentin, E
    Baillot-Rudoni, S
    Lalanne-Mistrich, ML
    Brun-Pacaud, A
    Petit, JM
    Brun, JM
    Gambert, P
    Vergès, B
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (10): : 5761 - 5764
1