Cells in Sol-Gels I: A Cytocompatible Route for the Production of Macroporous Silica Gels

被引：0
|
作者：
John F.T. Conroy
Mary E. Power
Jason Martin
Brian Earp
Bouvard Hosticka
Charles E. Daitch
Pamela M. Norris
机构：
[1] University of Virginia,Department of Mechanical and Aerospace Engineering
[2] University of Virginia,Department of Mechanical and Aerospace Engineering
来源：
Journal of Sol-Gel Science and Technology | 2000年 / 18卷
关键词：
bacteria; immobilization; sol-gel production; macroporous;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A novel, high hydrolysis ratio sol-gel route for the biocompatible production of macroporous silica gels is presented. This route exploits the two step nature of the gelation reaction to remove undesired alcohol by-products from an acidic aqueous sol prior to gelation. These alcohol-free sols will gel when the pH is raised to the physiologic range in a two-step, acid/base catalyzed process. Furthermore, monolithic macroporous samples can be produced in a controlled manner by introducing water-soluble organic polymers into the sol.
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页码：269 / 283
页数：14
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