Effect of growth factors on morphogenesis of human keratinocytes in vitro

被引:0
|
作者
K. Yu. Gnedeva
E. S. Chermnykh
E. A. Vorotelyak
A. V. Vasil’ev
V. V. Terskikh
机构
[1] Russian Academy of Sciences,Kol’tsov Institute of Developmental Biology
来源
Biology Bulletin | 2009年 / 36卷
关键词
Epidermal Growth Factor; Hepatocyte Growth Factor; Hair Follicle; Biology Bulletin; Dermal Papilla;
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中图分类号
学科分类号
摘要
The effect of some growth factors on morphogenetic processes in the primary culture of human epidermal keratinocytes was studied in the model of formation of tubule-like structures in collagen gel. Culturing of keratinocytes in the presence of IGF and bFGF did not induce growth of tubule-like structures, whereas EGF, KGF, and HGF promoted the growth of three-dimensional epidermal outgrowths whose shape and size varied depending on the growth factor used.
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页码:307 / 310
页数:3
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