Sleeping with the enemy: Clostridium difficile infection in the intensive care unit

被引：0
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作者：
Florian Prechter
Katrin Katzer
Michael Bauer
Andreas Stallmach
机构：
[1] Jena University Hospital,Department of Internal Medicine IV
[2] Jena University Hospital,Department of Anesthesiology and Intensive Care Medicine
[3] Center for Sepsis Control & Care,undefined
[4] Jena University Hospital,undefined
来源：
Critical Care | / 21卷
关键词：
infection; Management; Intensive care; Critical care; Severe infection; Treatment failure; Antibiotic-associated diarrhea;
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摘要：
Over the last years, there was an increase in the number and severity of Clostridium difficile infections (CDI) in all medical settings, including the intensive care unit (ICU). The current prevalence of CDI among ICU patients is estimated at 0.4–4% and has severe impact on morbidity and mortality. An estimated 10–20% of patients are colonized with C. difficile without showing signs of infection and spores can be found throughout ICUs. It is not yet possible to predict whether and when colonization will become infection. Figuratively speaking, our patients are sleeping with the enemy and we do not know when this enemy awakens.
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