A single inhibitor for all KRAS mutations

被引：0
|
作者：
Ryan B. Corcoran
机构：
[1] Harvard Medical School,Massachusetts General Hospital Cancer Center
来源：
Nature Cancer | 2023年 / 4卷
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摘要：
The recent design of mutation-selective KRAS inhibitors has led to US Food and Drug Administration approval of two inhibitors of KRAS(G12C), sotorasib and adagrasib. A study published in Nature reports the development of a first-in-class pan-KRAS-selective inhibitor. Here we comment on the current status of KRAS-targeting approaches.
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页码：1060 / 1062
页数：2
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