miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects

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作者
Chi Yang
Xiaohan Liu
Kai Zhao
Youming Zhu
Bin Hu
Yong Zhou
Mohan Wang
Yiqun Wu
Chengfei Zhang
Jianguang Xu
Yujie Ning
Duohong Zou
机构
[1] Shanghai Jiao Tong University School of Medicine,Department of Oral Surgery, Shanghai Key Laboratory of Stomatology, National Clinical Research Center of Stomatology, Ninth People’s Hospital
[2] Shanghai Jiao Tong University,Second Dental Clinic, Department of Oral Implantology, School of Medicine, Shanghai Key Laboratory of Stomatology, National Clinical Research Center of Stomatology. Ninth People’s Hospital
[3] Anhui Medical University,Department of Dental Implant Center, Stomatologic Hospital & College
[4] Key Laboratory of Oral Diseases Research of Anhui Province,Endodontology, Faculty of Dentistry
[5] University of Hong Kong,undefined
关键词
miRNA-21; BMSCs; PTEN/PI3K/Akt; Bone regeneration; Bone defects;
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