The incidence of type 1 diabetes in children under 15 years of age is rising again—a nationwide study

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作者
Edna F. Roche
Amanda M. McKenna
Myra O’Regan
Kerry J. Ryder
Helen M. Fitzgerald
Hilary M. C. V. Hoey
机构
[1] Trinity College Dublin,The Discipline of Paediatrics, School of Medicine
[2] The Research and Evidence Office,The Department of Paediatric Growth, Diabetes, and Endocrinology
[3] Health Service Executive,undefined
[4] Children’s Health Ireland (CHI) at,undefined
[5] Tallaght University Hospital,undefined
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Type 1 diabetes; Childhood; Incidence rate; Epidemiology;
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摘要
International incidence rates (IRs) and trends of childhood type 1 diabetes (T1D) vary. Recent data from Ireland and other high incidence countries suggested a stabilisation in IRs of T1D in children aged under 15 years. Our primary objective was to report the IR of T1D in children in Ireland from 2019 to 2021 and evaluate if age, sex and season of diagnosis had changed. Incident cases of T1D in those aged under 15 years were identified prospectively by clinicians nationally and reported to the Irish Childhood Diabetes National Register (ICDNR). Following case verification, capture-recapture methodology was applied, and IRs calculated. Numbers of children including age, sex and season of diagnosis per year were evaluated. There were 1027 cases, 542 males (53%). The direct standardised incidence rates (SIRs) increased by 21% overall and were 31.1, 32.2 and 37.6/100,000/year, respectively, with no significant sex difference. The highest IRs were in the 10–14-year category until 2021, then changed to the 5–9-year category (40% of cases). Whilst autumn and winter remain dominant diagnostic seasons, seasonality differed in 2021 with a greater number presenting in spring.
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页码:4615 / 4623
页数:8
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