The increased risk of sarcopenia in patients with cardiovascular risk factors in Suburb-Dwelling older Chinese using the AWGS definition

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Peipei Han
Hairui Yu
Yixuan Ma
Li Kang
Liyuan Fu
Liye Jia
Xiaoyu Chen
Xing Yu
Lin Hou
Lu Wang
Wen Zhang
Haifang Yin
Kaijun Niu
Qi Guo
机构
[1] TEDA International Cardiovascular Hospital,Department of Rehabilitation Medicine
[2] Cardiovascular Clinical College of Tianjin Medical University,Department of Rehabilitation Medicine
[3] Tianjin Medical University,Department of Cell Biology and Research Center of Basic Medical Science
[4] Tianjin Medical University,Nutritional Epidemiology Institute
[5] Tianjin Medical University,School of Public Health
[6] Tianjin Medical University,undefined
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The aim of the present study is to investigate the relationship between sarcopenia and cardiovascular risk factors (CVRF) in the Chinese elderly. A total of 1611 elderly individuals aged ≥60 years were enrolled in this study. The well-established CVRF of diabetes, hypertensions, and dyslipidemia were assessed. Sarcopenia was defined according to the recommended algorithm of the Asian Working Group for Sarcopenia (AWGS). Multiple logistic regression analyses and the linear regressions were used to evaluate the components of CVRF and the number of CVRF of elderly patients with sarcopenia. After adjusting for potential confounders, CVRF was associated with a high prevalence of sarcopenia in elderly Chinese populations. Furthermore, diabetes and hypertension, but not dyslipidemia, were found to be significantly associated with sarcopenia. The OR and 95% CI for sarcopenia of the participants with 1, 2, and 3 features of CVRF were 2.27(1.14–4.48), 4.13(1.80–9.46), and 4.90(1.01–23.81), respectively. A linear increase in the prevalence of sarcopenia was found to be associated with the number of CVRF components in the elderly population (P values for the trends < 0.001). Knowledge of known CVRF, particularly diabetes and hypertension, may help predict the risk for sarcopenia in the elderly.
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