A structural model for microtubule minus-end recognition and protection by CAMSAP proteins

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作者
Joseph Atherton
Kai Jiang
Marcel M Stangier
Yanzhang Luo
Shasha Hua
Klaartje Houben
Jolien J E van Hooff
Agnel-Praveen Joseph
Guido Scarabelli
Barry J Grant
Anthony J Roberts
Maya Topf
Michel O Steinmetz
Marc Baldus
Carolyn A Moores
Anna Akhmanova
机构
[1] Institute of Structural and Molecular Biology,Department of Biology
[2] Birkbeck,Division of Biology and Chemistry
[3] University of London,Department of Biology
[4] Cell Biology,Department of Computational Medicine and Bioinformatics
[5] Faculty of Science,Division of Biological Sciences
[6] Utrecht University,undefined
[7] Laboratory of Biomolecular Research,undefined
[8] Paul Scherrer Institut,undefined
[9] NMR Spectroscopy,undefined
[10] Bijvoet Center for Biomolecular Research,undefined
[11] Utrecht University,undefined
[12] Hubrecht Institute,undefined
[13] Royal Netherlands Academy of Arts and Sciences (KNAW),undefined
[14] Theoretical Biology and Bioinformatics,undefined
[15] Faculty of Science,undefined
[16] Utrecht University,undefined
[17] Molecular Cancer Research,undefined
[18] University Medical Center Utrecht,undefined
[19] University of Michigan Medical School,undefined
[20] University of California San Diego,undefined
[21] University of Basel,undefined
[22] Biozentrum,undefined
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摘要
Combined structural and microscopy approaches provide a model for how CAMSAP proteins recognize microtubule minus ends through their conserved CCK domains and protect microtubules from depolymerizing kinesin-13.
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页码:931 / 943
页数:12
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