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- [5] Demethoxycurcumin, bisdemethoxycurcumin, two natural derivatives of curcumin, attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NFκB signaling pathways in N9 microglia induced by lipopolysaccharide NEUROSCIENCE RESEARCH, 2010, 68 : E451 - E452