Sclerosing polycystic adenosis of parotid gland with dysplasia and ductal carcinoma in situReport of three cases with immunohistochemical and ultrastructural examination

被引:0
|
作者
A. Skálová
M. Michal
R. Simpson
I. Stárek
J. Přádná
M. Pfaltz
机构
[1] Department of Pathology,
[2] Medical Faculty of Charles University,undefined
[3] dr. E. Beneše 13,undefined
[4] 305 99 Plzeň,undefined
[5] Department of Pathology,undefined
[6] Royal Devon and Exeter Hospital,undefined
[7] Exeter,undefined
[8] Department of Otorhinolaryngology,undefined
[9] Medical Faculty,undefined
[10] Palacký University,undefined
[11] Olomouc,undefined
[12] Department of Pathology,undefined
[13] District Hospital České Budějovice,undefined
[14] Institute of Clinical Pathology,undefined
[15] University Hospital of Zürich,undefined
来源
Virchows Archiv | 2002年 / 440卷
关键词
Salivary gland Sclerosing polycystic adenosis Sialadenopathy Dysplasia Ductal carcinoma in situ;
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学科分类号
摘要
We describe three cases of sclerosing polycystic adenosis (SPA) of the parotid gland, a salivary condition analogous to fibrocystic disease of the breast. For the first time, immunoreactivity for oestrogen and progesterone receptors was demonstrated, suggesting a possible participation of hormone stimulation in its pathogenesis. In addition, all our cases showed foci of dysplasia of the ductal epithelium, which in one case was severe enough to amount to carcinoma in situ. This feature that has not previously been reported in SPA.
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页码:29 / 35
页数:6
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