Synthesis of New Thiazolo[3,2-b][1,2,4]triazole Derivatives and Preliminary Evaluation of Their Biological Activity

被引：0
|
作者：
A. P. Yengoyan
V. A. Pivazyan
E. A. Chazaryan
R. S. Hakobyan
机构：
[1] Russian-Armenian University,Pesticide Synthesis and Plant Protection Laboratory
[2] National Agrarian University of Armenia,undefined
来源：
Russian Journal of General Chemistry | 2019年 / 89卷
关键词：
thiazolo[3,2-; ][1,2,4]triazoles; 1-(6-methylthiazolo[3,2-; ][1,2,4]triazol-5-yl)ethan-1-one oxime; heterocyclization; growth regulating activity;
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学科分类号：
摘要：
Heterocyclization of 3-[(1H-1,2,4-triazol-3-yl)thio]pentane-2,4-dione afforded 1-(6-methylthiazolo[3,2-b][1,2,4]-triazol-5-yl)ethan-1-one, the reactions of which with hydroxylamine, hydrazincarboxamide, hydrazincarbothioamide, hydrazine hydrate and para-toluenesulfonyl hydrazide resulted in the formation of the corresponding derivatives. 1-(6-Methylthiazolo[3,2-b][1,2,4]triazol-5-yl)ethan-1-one oxime reacted with alkyl halides and phenyl isocyanate to produce the corresponding O-alkyl- and O-phenylcarbamoyl derivatives. The growth regulating activity of the compounds obtained was studied.
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页码：32 / 36
页数：4
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