Diagnostics of bronchopulmonary diseases through Mahalanobis distance-based absorption spectral analysis of exhaled air

被引：2
|
作者：
Bulanova A.A. [1 ]
Bukreeva E.B. [1 ]
Kistenev Y.V. [1 ,2 ]
Nikiforova O.Y. [3 ]
机构：
[1] Siberian State Medical University, Tomsk
[2] Tomsk State University, Tomsk
[3] V.E. Zuev Institute of Atmospheric Optics SB RAS, Tomsk
来源：
Frontiers of Optoelectronics | 2015年 / 8卷 / 2期
关键词：
bronchopulmonary diseases; CO[!sub]2[!/sub] laser; exhaled air; laser photo-acoustic spectroscopy; Mahalanobis distance;
D O I：
10.1007/s12200-015-0498-7
中图分类号：
学科分类号：
摘要：
Accurate diagnosis of different bronchopulmonary diseases is important in clinical practice. This study involved 20 healthy volunteers and 77 patients with bronchopulmonary diseases, including chronic obstructive pulmonary disease (COPD), bronchial asthma, pulmonary tuberculosis, and community-acquired pneumonia. The absorption spectrum of exhaled air samples was recorded on an intra-cavity photo-acoustic gas analyzer (ILPA-1, Special Technologies, Ltd., Russia) with photo-acoustic detectors and CO2 laser with a tuning range from 9.2 to 10.8 μm. In conclusion, analysis of the Mahalanobis distance-based absorption spectral profiles of breath air from bronchopulmonary patients and healthy volunteers allows the formulation of a preliminary diagnosis. © 2015, Higher Education Press and Springer-Verlag Berlin Heidelberg.
引用
收藏
页码：183 / 186
页数：3
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