New tricks for old NODs

被引：0
|
作者：
Eric M Pietras
Genhong Cheng
机构：
[1] University of California Los Angeles,Department of Microbiology, Immunology and Molecular Genetics
[2] University of California Los Angeles,Molecular Biology Institute
[3] University of California Los Angeles,Jonsson Comprehensive Cancer Center
来源：
Genome Biology | / 9卷
关键词：
Antiviral Response; Interferon Response; Interferon Signaling; Interferon Production; Card Domain;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Recent work has identified the human NOD-like receptor NLRX1 as a negative regulator of intracellular signaling leading to type I interferon production. Here we discuss these findings and the questions and implications they raise regarding the function of NOD-like receptors in the antiviral response.
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