Synthesis and Biological Activity of Arylcyclopentane-1-carboxylic Acids Aminoesters

被引：0
|
作者：
A. A. Aghekyan
G. G. Mkryan
A. S. Tsatinyan
G. V. Gasparyan
机构：
[1] Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia,A.L. Mnjoyan Institute of Fine Organic Chemistry
来源：
Russian Journal of General Chemistry | 2019年 / 89卷
关键词：
4-chlorophenylacetonitrile; arylcyclopentanecarboxylic acid; aminoalkylalkanol; amino esters;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
1-Arylcyclopentane-1-carboxylic acids were synthesized by alkaline hydrolysis of the corresponding nitriles. Reactions of the acid chlorides with N,N-dialkylaminoalkyl-and hetarylalkylalkanols provided new aminoester derivatives of 1-arylcyclopentane-1-carboxylic acids. Sympatholytic and adrenolytic activity of the obtained amino esters hydrochlorides was studied.
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页码：1051 / 1054
页数：3
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