Model of the RNA Polymerase Complex of the SARS-CoV-2 Virus with Favipiravir

被引：0
|
作者：
I. V. Polyakov
B. L. Grigorenko
A. V. Nemukhin
机构：
[1] Emanuel Institute of Biochemical Physics,
[2] Russian Academy of Sciences,undefined
[3] Moscow State University,undefined
来源：
Russian Journal of Physical Chemistry B | 2021年 / 15卷
关键词：
molecular dynamics; coronavirus; RNA polymerase; reaction mechanism; inhibition; favipiravir;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：103 / 107
页数：4
相关论文
共 50 条
  • [1] Model of the RNA Polymerase Complex of the SARS-CoV-2 Virus with Favipiravir
    Polyakov, I. V.
    Grigorenko, B. L.
    Nemukhin, A. V.
    RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B, 2021, 15 (01) : 103 - 107
  • [2] Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir
    Peng, Qi
    Peng, Ruchao
    Yuan, Bin
    Wang, Min
    Zhao, Jingru
    Fu, Lifeng
    Qi, Jianxun
    Shi, Yi
    INNOVATION, 2021, 2 (01):
  • [3] Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP
    Naydenova, Katerina
    Muir, Kyle W.
    Wu, Long-Fei
    Zhang, Ziguo
    Coscia, Francesca
    Peet, Mathew J.
    Castro-Hartmann, Pablo
    Qian, Pu
    Sader, Kasim
    Dent, Kyle
    Kimanius, Dari
    Sutherland, John D.
    Lowe, Jan
    Barford, David
    Russo, Christopher J.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (07)
  • [4] Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
    Ashleigh Shannon
    Barbara Selisko
    Nhung-Thi-Tuyet Le
    Johanna Huchting
    Franck Touret
    Géraldine Piorkowski
    Véronique Fattorini
    François Ferron
    Etienne Decroly
    Chris Meier
    Bruno Coutard
    Olve Peersen
    Bruno Canard
    Nature Communications, 11
  • [5] Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
    Shannon, Ashleigh
    Selisko, Barbara
    Nhung-Thi-Tuyet Le
    Huchting, Johanna
    Touret, Franck
    Piorkowski, Geraldine
    Fattorini, Veronique
    Ferron, Francois
    Decroly, Etienne
    Meier, Chris
    Coutard, Bruno
    Peersen, Olve
    Canard, Bruno
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [6] RNA polymerase: The Achilles heel of SARS-CoV-2
    Corteggiani, Marie
    Gombert, Lucas
    Pellegri, Callypso
    Aussel, Laurent
    M S-MEDECINE SCIENCES, 2021, 37 (03): : 288 - 292
  • [7] Favipiravir in SARS-CoV-2 Infection: Is it Worth it?
    Batiha, Gaber El-Saber
    Moubarak, Mohamed
    Shaheen, Hazem M.
    Zakariya, Ali M.
    Usman, Ibe M.
    Rauf, Abdur
    Adhikari, Achyut
    Dey, Abhijit
    Alexiou, Athanasios
    Hetta, Helal F.
    Al-Gareeb, Ali I.
    Al-kuraishy, Hayder M.
    COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 25 (14) : 2413 - 2428
  • [8] The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme
    Walker, Alexander P.
    Fan, Haitian
    Keown, Jeremy R.
    Knight, Michael L.
    Grimes, Jonathan M.
    Fodor, Ervin
    NUCLEIC ACIDS RESEARCH, 2021, 49 (22) : 13019 - 13030
  • [9] Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model
    Driouich, Jean-Selim
    Cochin, Maxime
    Lingas, Guillaume
    Moureau, Gregory
    Touret, Franck
    Petit, Paul-Remi
    Piorkowski, Geraldine
    Barthelemy, Karine
    Laprie, Caroline
    Coutard, Bruno
    Guedj, Jeremie
    de Lamballerie, Xavier
    Solas, Caroline
    Nougairede, Antoine
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [10] Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model
    Jean-Sélim Driouich
    Maxime Cochin
    Guillaume Lingas
    Grégory Moureau
    Franck Touret
    Paul-Rémi Petit
    Géraldine Piorkowski
    Karine Barthélémy
    Caroline Laprie
    Bruno Coutard
    Jérémie Guedj
    Xavier de Lamballerie
    Caroline Solas
    Antoine Nougairède
    Nature Communications, 12
12345