Adenylyl Cyclase-Associated Protein 1 in the Development of Head and Neck Squamous Cell Carcinomas

被引：0
|
作者：
G. V. Kakurina
I. V. Kondakova
O. V. Cheremisina
D. A. Shishkin
E. L. Choinzonov
机构：
[1] Tomsk Cancer Research Institute,
来源：
Bulletin of Experimental Biology and Medicine | 2016年 / 160卷
关键词：
actin-binding proteins; head and neck squamous cell carcinomas; differential diagnostics; adenylyl cyclase-associated protein 1; metastasizing;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We compared the content of adenylyl cyclase-associated protein 1 (CAP1) in the blood and tissues of patients with head and neck squamous cell carcinomas (with and without regional metastases), patients with chronic inflammatory diseases aggravated by laryngeal and laryngopharyngeal dysplasia, and healthy individuals. The data suggest that serum CAP1 concentration correlated with the depth of primary tumor invasion and the presence of regional metastases. In cancer patients, the serum level of CAP1 was lower than in patients with laryngeal and laryngopharyngeal dysplasia, which can be of importance for differential and timely diagnostics of malignant tumors.
引用
下载
收藏
页码：695 / 697
页数：2
相关论文
共 50 条
  • [1] Adenylyl Cyclase-Associated Protein 1 in the Development of Head and Neck Squamous Cell Carcinomas
    Kakurina, G. V.
    Kondakova, I. V.
    Cheremisina, O. V.
    Shishkin, D. A.
    Choinzonov, E. L.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2016, 160 (05) : 695 - 697
  • [2] Adenylyl Cyclase-Associated Protein 1 in Metastasis of Squamous Cell Carcinoma of the Head and Neck and Non-Small Cell Lung Cancer
    Kakurina, G. V.
    Kolegova, E. S.
    Cheremisina, O. V.
    Zavyalov, A. A.
    Shishkin, D. A.
    Kondakova, I. V.
    Choinzonov, E. L.
    PHYSICS OF CANCER: INTERDISCIPLINARY PROBLEMS AND CLINICAL APPLICATIONS (PC'16), 2016, 1760
  • [3] Effect of association with adenylyl cyclase-associated protein on the interaction of yeast adenylyl cyclase with Ras protein
    Shima, F
    YamawakiKataoka, Y
    Yanagihara, C
    Tamada, M
    Okada, T
    Kariya, K
    Kataoka, T
    MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (03) : 1057 - 1064
  • [4] Adenylyl Cyclase-Associated Protein 1: Structure, Regulation, and Participation in Cellular Processes
    Kakurina, G. V.
    Kolegova, E. S.
    Kondakova, I. V.
    BIOCHEMISTRY-MOSCOW, 2018, 83 (01) : 45 - 53
  • [5] Adenylyl cyclase-associated protein 1: Structure, regulation, and participation in cellular processes
    G. V. Kakurina
    E. S. Kolegova
    I. V. Kondakova
    Biochemistry (Moscow), 2018, 83 : 45 - 53
  • [6] Squamous cell carcinomas of the head and neck
    Sanderson, RJ
    Ironside, JAD
    BMJ-BRITISH MEDICAL JOURNAL, 2002, 325 (7368): : 822 - 827
  • [7] Squamous cell carcinomas of the head and neck
    Demard, F.
    Schneider, M.
    ONCOLOGIE, 2009, 11 (03) : 115 - 115
  • [8] Development of targeted therapy for squamous cell carcinomas of the head and neck
    Burgos-Tiburcio, Alberto
    Santos, Edgardo S.
    Arango, Belisario A.
    Raez, Luis E.
    EXPERT REVIEW OF ANTICANCER THERAPY, 2011, 11 (03) : 373 - 386
  • [9] Characterization of a Peptide Antibody Specific to the Adenylyl Cyclase-Associated Protein of Acanthamoeba castellanii
    Kim, Min-Jeong
    Lee, Hae-Ahm
    Quan, Fu-Shi
    Kong, Hyun-Hee
    Moon, Eun-Kyung
    KOREAN JOURNAL OF PARASITOLOGY, 2022, 60 (01): : 7 - 14
  • [10] Mammalian Adenylyl Cyclase-associated Protein 1 (CAP1) Regulates Cofilin Function, the Actin Cytoskeleton, and Cell Adhesion
    Zhang, Haitao
    Ghai, Pooja
    Wu, Huhehasi
    Wang, Changhui
    Field, Jeffrey
    Zhou, Guo-Lei
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (29) : 20966 - 20977
12345