Reproducibility of urinary bisphenol A concentrations measured during pregnancy in the Generation R Study

被引：0

作者：

Todd A Jusko

Pamela A Shaw

Claudia A Snijder

Frank H Pierik

Holger M Koch

Russ Hauser

Vincent W V Jaddoe

Alex Burdorf

Albert Hofman

Henning Tiemeier

Matthew P Longnecker

机构：

[1] University of Rochester School of Medicine and Dentistry,Department of Public Health Sciences

[2] 265 Crittenden Boulevard,Department of Biostatistics and Epidemiology

[3] University of Pennsylvania Perelman School of Medicine,Department of Public Health

[4] 423 Guardian Drive,Department of Urban Environment and Safety

[5] Erasmus Medical Center,Department of Environmental Health

[6] The Generation R Study Group,Department of Epidemiology

[7] Erasmus Medical Center,Department of Pediatrics

[8] Erasmus Medical Centre,Department of Child and Adolescent Psychiatry

[9] TNO (Netherlands Organization for Applied Scientific Research),undefined

[10] Princetonlaan 6,undefined

[11] Institute for Prevention and Occupational Medicine of the German Social Accident Insurance,undefined

[12] Institute of Ruhr-University Bochum,undefined

[13] Bürkle-de-la-Camp-Platz 1,undefined

[14] Harvard School of Public Health,undefined

[15] 665 Huntington Avenue,undefined

[16] Erasmus Medical Center,undefined

[17] Erasmus Medical Center,undefined

[18] Erasmus Medical Center,undefined

[19] Epidemiology Branch,undefined

[20] National Institute of Environmental Health Sciences,undefined

[21] NIH,undefined

[22] 111 T.W. Alexander Drive,undefined

[23] Research Triangle Park,undefined

来源：

Journal of Exposure Science & Environmental Epidemiology | 2014年 / 24卷

关键词：

endocrine disruptor; epidemiology; environmental exposure; intraclass correlation coefficient; misclassification;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The potential human health effects of bisphenol A (BPA) exposure are a public health concern. In order to design adequately powered epidemiological studies to address potential health effects, data on the reproducibility of BPA concentration in serial urine specimens taken during pregnancy are needed. To provide additional data on the reproducibility of maternal urine specimens, 80 women in the Generation R Study (Rotterdam, The Netherlands) contributed a spot urine specimen at <18, 18–25, and >25 weeks of pregnancy. Reproducibility, estimated by the intraclass correlation coefficient (ICC), was 0.32 (95% confidence interval: 0.18–0.46), and, on a creatinine basis, 0.31 (95% confidence interval: 0.16–0.47). Although the ICC observed in the Generation R Study is slightly higher than previous reproducibility studies of BPA, it nevertheless indicates a high degree of within-person variability that presents challenges for designing well-powered epidemiologic studies.

引用

页码：532 / 536

页数：4

共 50 条

[1] Reproducibility of urinary bisphenol A concentrations measured during pregnancy in the Generation R Study
Jusko, Todd A.
Shaw, Pamela A.
Snijder, Claudia A.
Pierik, Frank H.
Koch, Holger M.
Hauser, Russ
Jaddoe, Vincent W. V.
Burdorf, Alex
Hofman, Albert
Tiemeier, Henning
Longnecker, Matthew R.
[J]. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 2014, 24 (05) : 532 - 536
[2] Urinary Concentrations of Bisphenol A and Phthalate Metabolites Measured during Pregnancy and Risk of Preeclampsia
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[J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 124 (10) : 1651 - 1655
[3] Variability and Predictors of Urinary Bisphenol A Concentrations during Pregnancy
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[4] Urinary Concentrations of Bisphenol Mixtures during Pregnancy and Birth Outcomes: The MAKE Study
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[J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (19)
[5] Variability of Urinary Phthalate Metabolite and Bisphenol A Concentrations before and during Pregnancy
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[6] Thyroid hormone parameters during pregnancy in relation to urinary bisphenol A concentrations: A repeated measures study
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[7] A possible approach to improving the reproducibility of urinary concentrations of phthalate metabolites and phenols during pregnancy
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