The systems biology of signaling pathways

被引：3
|
作者：
Lavrik I.N. [1 ,2 ]
Samsonova M.G. [3 ]
机构：
[1] Otto-von-Guericke University, Magdeburg
[2] Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, pr. Lavrent’eva 10, Novosibirsk
[3] Peter the Great St. Petersburg Polytechnic University, ul. Polytekhnicheskaya 29, St. Petersburg
来源：
Biophysics | 2016年 / 61卷 / 1期
关键词：
apoptosis; mathematical modeling; signaling pathways; systems biology;
D O I：
10.1134/S0006350916010127
中图分类号：
学科分类号：
摘要：
Signaling networks play the central role in the regulation of processes in a single cell and in the entire body. A recent breakthrough in technologies for systems biology, which combine experimental and mathematical methods, permits scientists to model signaling pathways in an individual cell and in cell populations. This approach provides new information on mechanisms that regulate a variety of biological processes. Here we discuss the mathematical formalisms that are applied to signaling pathway modeling and relevant experimental methods. © 2016, Pleiades Publishing, Inc.
引用
收藏
页码：78 / 84
页数：6
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