Fine tuning of immunometabolism for the treatment of rheumatic diseases

被引：0

作者：

Jillian P. Rhoads

Amy S. Major

Jeffrey C. Rathmell

机构：

[1] Microbiology,Jillian P. Rhoads is at the Division of Molecular Pathology, Department of Pathology

[2] and Immunology,Amy S. Major is at the Division of Molecular Pathology, Department of Pathology, Vanderbilt University Medical Center; the Division of Rheumatology and Immunology, Department of Medicine, USA; and at the Department for Veterans Affairs

[3] Vanderbilt University Medical Center,the Division of Rheumatology and Immunology, Department of Medicine

[4] 1161 21st Avenue South,Division of Molecular Pathology, Department of Pathology

[5] Nashville,undefined

[6] Tennessee 37232,undefined

[7] USA.,undefined

[8] Microbiology,undefined

[9] and Immunology,undefined

[10] Vanderbilt University Medical Center; and the Vanderbilt Center for Immunobiology,undefined

[11] Vanderbilt University School of Medicine,undefined

[12] 1161 21st Avenue South,undefined

[13] Nashville,undefined

[14] Tennessee 37232,undefined

[15] Tennessee Valley Healthcare System,undefined

[16] Nashville,undefined

[17] Tennessee 37232,undefined

[18] USA.,undefined

[19] Vanderbilt University Medical Center,undefined

[20] Microbiology,undefined

[21] and Immunology,undefined

[22] and the Vanderbilt Center for Immunobiology,undefined

[23] Vanderbilt University School of Medicine,undefined

来源：

Nature Reviews Rheumatology | 2017年 / 13卷

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摘要：

The pathways by which cells modulate metabolism to attain optimal effector responses present numerous potential therapeutic targets in the context of rheumatic diseases. This article explores the ways in which selective manipulation of metabolic pathways might influence immune cell populations and provide protection from inflammation and disease.

引用

页码：313 / 320

页数：7

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