Antimicrobial Stewardship and Environmental Decontamination for the Control of Clostridium difficile Transmission in Healthcare Settings

被引：0
|
作者：
Jason Bintz
Suzanne Lenhart
Cristina Lanzas
机构：
[1] Houghton College,Department of Mathematics
[2] University of Tennessee,Department of Mathematics
[3] North Carolina State University,Department of Population Health and Pathobiology
来源：
Bulletin of Mathematical Biology | 2017年 / 79卷
关键词：
Control; Agent-based model;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We implement an agent-based model for Clostridium difficile transmission in hospitals that accounts for several processes and individual factors including environmental and antibiotic heterogeneity in order to evaluate the efficacy of various control measures aimed at reducing environmental contamination and mitigating the effects of antibiotic use on transmission. In particular, we account for local contamination levels that contribute to the probability of colonization and we account for both the number and type of antibiotic treatments given to patients. Simulations illustrate the relative efficacy of several strategies for the reduction of nosocomial colonizations and nosocomial diseases.
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页码：36 / 62
页数：26
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