Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol

被引：0
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作者：
Jonas E. Svensson
Martin Bolin
Daniel Thor
Pete A. Williams
Rune Brautaset
Marcus Carlsson
Peder Sörensson
David Marlevi
Rubens Spin-Neto
Monika Probst
Göran Hagman
Anton Forsberg Morén
Miia Kivipelto
Pontus Plavén-Sigray
机构：
[1] Karolinska Institutet and Stockholm Health Care Services,Department of Clinical Neuroscience, Centre for Psychiatry Research
[2] Karolinska University Hospital,Theme Inflammation and Aging
[3] Karolinska University Hospital,Department of Medical Radiation Physics and Nuclear Medicine
[4] Karolinska Institutet,Department of Oncology
[5] St. Erik Eye Hospital,Pathology
[6] Karolinska Institutet,Department of Clinical Neuroscience, Division of Eye and Vision
[7] Karolinska Institutet,Department of Molecular Medicine and Surgery
[8] Karolinska Institutet,Department of Medicine Solna
[9] Massachusetts Institute of Technology,Institute for Medical Engineering and Science
[10] Aarhus University,Department of Dentistry and Oral Health, Section for Oral Radiology
[11] Technical University of Munich,Department of Diagnostic and Interventional Neuroradiology, Klinikum Rechts Der Isar, School of Medicine
[12] Karolinska Institutet,Department of Neurobiology, Care Sciences, and Society, Division of Clinical Geriatrics
[13] Imperial College London,Ageing Epidemiology Research Unit (AGE), School of Public Health, Faculty of Medicine
[14] University of Eastern Finland,Institute of Public Health and Clinical Nutrition
[15] Copenhagen University Hospital,Neurobiology Research Unit
来源：
BMC Neurology | / 24卷
关键词：
Rapamycin; Sirolimus; Alzheimer’s disease; Clinical trial; PET; MRI; CT; OCT; Geroprotection; Aging;
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