hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation

被引：0
|
作者：
Yun Chang
Ya-nan Li
Rui Bai
Fujian Wu
Shuhong Ma
Amina Saleem
Siyao Zhang
Youxu Jiang
Tao Dong
Tianwei Guo
Chengwen Hang
Wen-jing Lu
Hongfeng Jiang
Feng Lan
机构：
[1] Beijing Anzhen Hospital,Beijing Laboratory for Cardiovascular Precision Medicine, The Key Laboratory of Biomedical Engineering for Cardiovascular Disease Research, The Key Laboratory of Remodeling
[2] Capital Medical University,Related Cardiovascular Disease, Ministry of Education
[3] Beijing Institute of Heart,Department of Cardiology
[4] Lung and Blood Vessel Diseases,State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Key Laboratory of Application of Pluripotent Stem Cells in Heart Regeneration
[5] Peking University Third Hospital,undefined
[6] Chinese Academy of Medical Sciences and Peking Union Medical College,undefined
来源：
Stem Cell Research & Therapy | / 12卷
关键词：
Human ether-a-go-go-related gene; hESCs; QT prolongation; CRISPR/Cas9;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation
    Chang, Yun
    Li, Ya-nan
    Bai, Rui
    Wu, Fujian
    Ma, Shuhong
    Saleem, Amina
    Zhang, Siyao
    Jiang, Youxu
    Dong, Tao
    Guo, Tianwei
    Hang, Chengwen
    Lu, Wen-jing
    Jiang, Hongfeng
    Lan, Feng
    [J]. STEM CELL RESEARCH & THERAPY, 2021, 12 (01)
  • [2] KCNQ1-deficient and KCNQ1-mutant human embryonic stem cell-derived cardiomyocytes for modeling QT prolongation
    Yuanxiu Song
    Tianwei Guo
    Youxu Jiang
    Min Zhu
    Hongyue Wang
    Wenjing Lu
    Mengqi Jiang
    Man Qi
    Feng Lan
    Ming Cui
    [J]. Stem Cell Research & Therapy, 13
  • [3] KCNQ1-deficient and KCNQ1-mutant human embryonic stem cell-derived cardiomyocytes for modeling QT prolongation
    Song, Yuanxiu
    Guo, Tianwei
    Jiang, Youxu
    Zhu, Min
    Wang, Hongyue
    Lu, Wenjing
    Jiang, Mengqi
    Qi, Man
    Lan, Feng
    Cui, Ming
    [J]. STEM CELL RESEARCH & THERAPY, 2022, 13 (01)
  • [4] Human embryonic stem cell-derived cardiomyocytes as a model for assessing HERG channel blockade
    Terracciano, C. M. N.
    Payne, J.
    Harding, S. E.
    Ali, N. N.
    [J]. HEART, 2008, 94 (02)
  • [5] The electrocardiogram of human embryonic stem cell-derived cardiomyocytes
    Reppel, M
    Pillekamp, F
    Brockmeier, K
    Matzkies, M
    Bekcioglu, A
    Lipke, T
    Nguemo, F
    Bonnemeier, H
    Hescheler, J
    [J]. JOURNAL OF ELECTROCARDIOLOGY, 2005, 38 (04) : 166 - 170
  • [6] Availability of human induced pluripotent stem cell-derived cardiomyocytes in assessment of drug potential for QT prolongation
    Nozaki, Yumiko
    Honda, Yayoi
    Tsujimoto, Shinji
    Watanabe, Hitoshi
    Kunimatsu, Takeshi
    Funabashi, Hitoshi
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 278 (01) : 72 - 77
  • [7] Responses to endothelin in human embryonic stem cell-derived cardiomyocytes
    Wright, Jamie
    Ahmet, Selda
    Harding, Sian E.
    Ali, Nadire N.
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2007, 42 : S88 - S88
  • [8] Functional Properties of Human Embryonic Stem Cell-Derived Cardiomyocytes
    Zeevi-Levin, Naama
    Itskovitz-Eldor, Joseph
    Binah, Ofer
    [J]. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION, 2010, 20 (01): : 51 - 59
  • [9] Potential applications of human embryonic stem cell-derived cardiomyocytes
    Caspi, O
    Gepstein, L
    [J]. CARDIAC ENGINEERING: FROM GENES AND CELLS TO STRUCTURE AND FUNCTION, 2004, 1015 : 285 - 298
  • [10] Differentiation pathways in human embryonic stem cell-derived cardiomyocytes
    Lev, S
    Kehat, I
    Gepstein, L
    [J]. COMMUNICATIVE CARDIAC CELL, 2005, 1047 : 50 - 65
12345