Structural studies and antimicrobial properties of norcembrane diterpenoid from an Indian soft coral Sinularia inelegans Tixier-Durivault

被引：0

作者：

Keisham Sarjit Singh

Werner H. Kaminsky

Celina Rodrigues

C. G. Naik

机构：

[1] National Institute of Oceanography (CSIR),Bioorganic Chemistry Laboratory

[2] University of Washington,Department of Chemistry

来源：

Journal of Chemical Sciences | 2009年 / 121卷

关键词：

Diterpene; sinularia; stereochemistry; antimicrobial; crystallography;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Two metabolites featuring norcembranoid diterpene skeleton have been isolated from chloroform extract of soft coral of the genus sinularia, which was collected from the southern coast of India. The structures of the metabolites were determined by 1D, 2D NMR spectroscopic data and HRESIMS data analysis. The compounds have shown moderate-to-high antimicrobial activities. The structure and the relative stereochemistry of the metabolite 1 have been determined by X-ray crystallography.

引用

页码：1041 / 1046

页数：5

共 16 条

[1] Structural studies and antimicrobial properties of norcembrane diterpenoid from an Indian soft coral Sinularia inelegans Tixier-Durivault
Singh, Keisham Sarjit
Kaminsky, Werner H.
Rodrigues, Celina
Naik, C. G.
JOURNAL OF CHEMICAL SCIENCES, 2009, 121 (06) : 1041 - 1046
[2] Sterols from the soft coral Sinularia depressa Tixier-Durivault
Zhang, Guang-Wen
Ma, Xiang-Quan
Su, Jing-Yu
Zeng, Long-Mei
Zhongshan Daxue Xuebao/Acta Scientiarum Natralium Universitatis Sunyatseni, 2003, 42 (02):
[3] Bioactive polyhydroxylated steroids from the Hainan soft coral Sinularia depressa Tixier-Durivault
Liang, Lin-Fu
Wang, Xu-Jie
Zhang, Hai-Yan
Liu, Hai-Li
Li, Jia
Lan, Le-Fu
Zhang, Wen
Guo, Yue-Wei
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (05) : 1334 - 1337
[4] Diterpenes from the Hainan Soft Coral Lobophytum cristatum Tixier-Durivault
Li, Liang
Sheng, Li
Wang, Chang-Yun
Zhou, Yu-Bo
Huang, Hui
Li, Xiu-Bao
Li, Jia
Mollo, Ernesto
Gavagnin, Margherita
Guo, Yue-Wei
JOURNAL OF NATURAL PRODUCTS, 2011, 74 (10): : 2089 - 2094
[5] METABOLITES OF THE SOUTH ANDAMAN SOFT CORAL SINULARIA-CONFERTA DANA SENSU TIXIER-DURIVAULT 1951
SUBRAHMANYAM, C
RAO, CV
KOBAYASHI, M
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1993, 32 (12): : 1298 - 1299
[6] DPPH Scavenging Property of Active Principles from Soft Coral Sarcophyton Flexuosum Tixier-Durivault
Byju, K.
Anuradha, V.
Rosmine, Emilda
Sankar, H. S. Hari
Gopinath, Anu
Peter, K. J. Prashob
Kumar, T. R. Gireesh
Vasundhara, G.
Kumar, N. C.
Nair, S. M.
PHARMACEUTICAL CHEMISTRY JOURNAL, 2015, 49 (03) : 178 - 182
[7] DPPH Scavenging Property of Active Principles from Soft Coral Sarcophyton Flexuosum Tixier-Durivault
K. Byju
V. Anuradha
Emilda Rosmine
H. S. Hari Sankar
Anu Gopinath
K. J. Prashob Peter
T. R. Gireesh Kumar
G. Vasundhara
N. C. Kumar
S. M. Nair
Pharmaceutical Chemistry Journal, 2015, 49 : 178 - 182
[8] A novel furanosesquiterpenoid from the soft coral Lobophytum catalai Tixier-Durivault of the Andaman and Nicobar Islands
Anjaneyulu, ASR
Rao, NSK
Venugopal, MJRV
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1996, 35 (10): : 1001 - 1003
[9] Two new cembranoids from the soft coral Lobophytum catalai Tixier-Durivault of the Andaman and Nicobar Islands
Anjaneyulu, ASR
Rao, NSK
Sagar, KS
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1998, 37 (03): : 267 - 274
[10] Pambanolides A-C from the South Indian soft coral Sinularia inelegans
Chitturi, Bhujanga Rao
Tatipamula, Vinay Bharadwaj
Dokuburra, Chanti Babu
Mangamuri, Usha Kiranmayi
Tuniki, Venugopal Raju
Kalivendi, Shasi Vardhan
Bunce, Richard A.
Yenamandra, Venkateswarlu
TETRAHEDRON, 2016, 72 (16) : 1933 - 1940

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